The smart Trick of ceesdekker That No One is Discussing
The smart Trick of ceesdekker That No One is Discussing
Blog Article
2009, discovery of a completely new phenotype for bacteria in narrow nanofluidic slits; and very first detection of regional protein constructions alongside DNA applying solid-state nanopores
It had been only in the nineties though, when nanotechnology experienced advanced into a level the place one molecules could possibly be manipulated, that the main experimental units commenced to seem.
Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
Due to the fact 2000, Dekker has shifted the primary emphasis of his work in the direction of biophysics wherever he scientific tests the properties of solitary biomolecules and cells using the instruments of nanotechnology. This change of area was driven by his fascination for that remarkable functioning of biological molecular constructions, together with via the extended-expression standpoint that numerous interesting discoveries could be anticipated With this subject.[five] Present-day strains of research in his biophysics group are within the areas of:[6]
This yielded a breakthrough. In just just a few months, we were being capable to measure transport via somebody single-walled carbon nanotube. Based upon minimal-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Know-how with the Energetic research lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were authentic quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic behaviour.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
‘In the beginning we checked out Organic systems by using a Actual physical view and acted on The idea with the tools we realized. It took a few years before we started out Performing more on the big biological troubles. I then began to call it nanobiology, a term that didn't exist at time.
2011, 1st in vitro measurements of transportation across just one biomimetic nuclear pore complicated; improvement of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination
You might help our author matching procedure! When you observe any publications incorrectly attributed to this author, be sure to check in and mark matches as appropriate or incorrect.
Pretty interesting, but that wasn’t definitely where my fascination lay. I wanted to pioneer And that i experienced the feeling which was no more attainable, since the most interesting fundamental insights experienced by now been uncovered. But my industry had designed many remarkable new resources to measure particular person molecules. I made a decision that I desired to use this to biology, to take a look at it from the physical standpoint.’
In 1993 he was appointed as Associate Professor at Delft College of Technological innovation. Inside the mid-nineteen nineties Dekker and his staff attained achievement with the invention on the electronic Attributes of carbon nanotubes, the 1st solitary-molecule transistor as well as other nanoscience.
2006, first demonstration of molecular sorting in the lab with a chip utilizing biomotors; discovery of nanobubbles in reliable-point out nanopores; and first estimate of electrokinetic Vitality conversion in a very nanofluidic channel
Developments in nanotechnology in the 1990s produced creating electronic gadgets from single molecules a chance. Cees Dekker recounts how his group developed a area-temperature transistor determined by one carbon nanotube.
It had been a very exciting time, all through which I obtained many assistance from Delft University of ceesdekker Technological know-how, in which I used to be a professor at some time, And that i started out various collaborations with molecular biologists. That helped me find out quite a bit.’